role of polyunsaturated fatty acids in cardiovascular diseases

نویسندگان

mohammad asif department of pharmacy, grd (pg) imt, dehradun, india.

چکیده

polyunsaturated fatty acids (pufas) particularly ω-3 pufas showed great assure in prevention of cardiovascular diseases (cvd). the evidence for cv benefits of pufa comes from eicosapentaenoic acid (epa) with or without docosahexaenoic acid (dha) in primary prevention, after myocardial infarction (mi), with heart failure (hf). the epidemiologic studies and trials showing the benefits of pufa, specifically epa and dha, in cv prevention and provide potential mechanisms. the target epa and dha consumption should be at least 500 mg/day for individuals without basic evident cv disease and at least 800 to 1,000 mg/day for individuals with known coronary heart disease (chd) and heart failure (hf) and optimal dosing and relative ratio of dha and epa ω-3 pufa that provides maximum cardio-protection at risk of cvd as well in treatment of atherosclerotic, arrhythmic, and primary myocardial disorders.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Omega-3 polyunsaturated fatty acids and cardiovascular diseases.

Omega-3 polyunsaturated fatty acid (omega-3 PUFA) therapy continues to show great promise in primary and, particularly in secondary prevention of cardiovascular (CV) diseases. The most compelling evidence for CV benefits of omega-3 PUFA comes from 4 controlled trials of nearly 40,000 participants randomized to receive eicosapentaenoic acid (EPA) with or without docosahexaenoic acid (DHA) in stu...

متن کامل

Polyunsaturated fatty acids and inflammatory diseases.

Inflammation is overall a protective response, whose main goal is to liberate the human being of cellular lesions caused by micro-organisms, toxins, allergens, etc., as well as its consequences, and of death cells and necrotic tissues. Chronic inflammation, which is detrimental to tissues, is the basic pathogenic mechanism of hypersensitivity reactions against xenobiotics. Other frequent pathol...

متن کامل

Metabolic Effects of Polyunsaturated Fatty Acids in Chickens: A Review

Chicken has been used as a suitable model for lipid metabolism studies, because dietary modifications especially dietary fat type can change chicken body composition. Fats act as a condense source of energy and certain fatty acids such as polyunsaturated fatty acids (PUFAs) are required for both animal and human health. The n-3 PUFAs, especially, eicosapentaenoic acid (EPA) and docosahexaenoic ...

متن کامل

Effect of omega-3 polyunsaturated fatty acids and vitamin D on cardiovascular diseases.

PuFA = polyunsaturated fatty acids CVD = cardiovascular disease omega-3 PuFa Most of the evidence of the benefits of omega-3 PUFA was obtained for long-chain fatty acids, eicosapentaenoic acid and docosahexaenoic acid, the active components of fish oils [1]. Humans get omega-3 PUFA from fish oils. The original source of the omega-3 found in fish oils is marine microorganisms. The current Americ...

متن کامل

[Role of omega-3 polyunsaturated fatty acids in diet of patients with rheumatic diseases].

The beneficial effects of omega-3 polyunsaturated fatty acids have been widely described in the literature in particular those on cardiovascular system. In the last decade there has been an increased interest in the role of these nutrients in the reduction of articular inflammation as well as in the improvement of clinical symptoms in subjects affected by rheumatic diseases, in particular rheum...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of pharmaceutical care

جلد ۲، شماره ۱، صفحات ۳۷-۴۴

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023